Steven K Grinspoon Selected Research

Biomarkers (Surrogate Marker)

1/2021	Growth Hormone Releasing Hormone Reduces Circulating Markers of Immune Activation in Parallel with Effects on Hepatic Immune Pathways in Individuals with HIV-infection and Nonalcoholic Fatty Liver Disease.
1/2021	Assessment of Coronary Artery Disease With Computed Tomography Angiography and Inflammatory and Immune Activation Biomarkers Among Adults With HIV Eligible for Primary Cardiovascular Prevention.
1/2021	Altered pattern of circulating miRNAs in HIV lipodystrophy perturbs key adipose differentiation and inflammation pathways.
1/2019	Serum Lipocalin 2 (Neutrophil Gelatinase-Associated Lipocalin) in Relation to Biomarkers of Inflammation and Cardiac Stretch During Activation of the Renin-Angiotensin-Aldosterone System in Human Immunodeficiency Virus.
1/2019	Diet Quality Is Low and Differs by Sex in People with HIV.
1/2019	Caspase-1 Activation Is Related With HIV-Associated Atherosclerosis in an HIV Transgenic Mouse Model and HIV Patient Cohort.
1/2019	Rationale and design of the Mechanistic Substudy of the Randomized Trial to Prevent Vascular Events in HIV (REPRIEVE): Effects of pitavastatin on coronary artery disease and inflammatory biomarkers.
1/2019	Relationship of visceral and subcutaneous adipose depots to markers of arterial injury and inflammation among individuals with HIV.
9/2018	Assessing statin effects on cardiovascular pathways in HIV using a novel proteomics approach: Analysis of data from INTREPID, a randomized controlled trial.
1/2018	Brief Report: Statin Effects on Myocardial Fibrosis Markers in People Living With HIV.

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Steven K Grinspoon Research Topics

Disease

23	Cardiovascular Diseases (Cardiovascular Disease) 10/2022 - 04/2006
20	Inflammation (Inflammations) 01/2021 - 04/2006
19	HIV Infections (HIV Infection) 01/2021 - 04/2003
19	Insulin Resistance 01/2021 - 04/2005
14	Obesity 12/2021 - 05/2006
13	Atherosclerosis 10/2022 - 08/2011
10	Coronary Artery Disease (Coronary Atherosclerosis) 01/2021 - 01/2010
9	Metabolic Syndrome (Dysmetabolic Syndrome X) 12/2021 - 04/2006
7	Fibrosis (Cirrhosis) 01/2021 - 10/2016
7	Non-alcoholic Fatty Liver Disease 01/2021 - 04/2016
6	Lipodystrophy 01/2021 - 09/2006
6	Dyslipidemias (Dyslipidemia) 09/2018 - 04/2005
5	Arteritis 11/2022 - 02/2015
5	Infections 01/2022 - 11/2002
5	Myocardial Infarction 01/2019 - 04/2005
5	Atherosclerotic Plaque (Atheroma) 01/2019 - 07/2010
4	Hypertension (High Blood Pressure) 12/2021 - 04/2005
4	Acquired Immunodeficiency Syndrome (AIDS) 01/2019 - 11/2002
4	Hyperinsulinism (Hyperinsulinemia) 01/2017 - 02/2004
3	Stroke (Strokes) 01/2019 - 08/2012
2	Heart Diseases (Heart Disease) 01/2022 - 07/2012
2	Heart Failure 01/2020 - 01/2019
2	Overweight 11/2018 - 12/2009
2	Fatty Liver 10/2018 - 12/2017
2	Abdominal Obesity 10/2017 - 04/2006
1	COVID-19 01/2022
1	Hypertriglyceridemia 01/2021
1	Liver Diseases (Liver Disease) 01/2021
1	Hepatocellular Carcinoma (Hepatoma) 01/2020
1	Cardiac Sudden Death (Sudden Cardiac Arrest) 01/2019
1	Pulmonary Hypertension 01/2019

Drug/Important Bio-Agent (IBA)

14	Biomarkers (Surrogate Marker)IBA 01/2021 - 07/2007
14	Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA 01/2021 - 04/2005
11	Glucose (Dextrose)FDA LinkGeneric 12/2021 - 11/2002
11	LipidsIBA 05/2018 - 11/2005
9	AdiponectinIBA 01/2021 - 04/2003
9	oxidized low density lipoproteinIBA 01/2019 - 02/2012
7	AldosteroneIBA 11/2022 - 11/2009
7	tesamorelin FDA Link 01/2021 - 01/2011
6	Insulin (Novolin)FDA Link 11/2018 - 04/2005
5	LDL CholesterolIBA 12/2021 - 02/2015
5	Growth Hormone-Releasing Hormone (Somatotropin Releasing Hormone)IBA 01/2021 - 01/2011
5	pitavastatin (itavastatin)FDA Link 01/2020 - 01/2017
5	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2019 - 04/2006
4	1-Alkyl-2-acetylglycerophosphocholine Esterase (PAF Acetylhydrolase)IBA 11/2022 - 10/2016
4	Growth Hormone (Somatotropin)IBA 01/2021 - 12/2009
4	Proteins (Proteins, Gene)FDA Link 10/2020 - 01/2017
4	Atorvastatin (Lipitor)FDA Link 03/2020 - 02/2015
4	C-Reactive ProteinIBA 01/2019 - 04/2006
4	CholesterolIBA 01/2018 - 09/2006
4	Etanercept (Enbrel)FDA Link 01/2011 - 04/2006
3	Hormones (Hormone)IBA 01/2021 - 10/2018
3	Insulin-Like Growth Factor I (IGF-1)IBA 01/2021 - 01/2009
3	Interleukin-6 (Interleukin 6)IBA 01/2021 - 04/2006
3	MicroRNAs (MicroRNA)IBA 01/2021 - 08/2014
3	Lipopolysaccharide ReceptorsIBA 01/2018 - 01/2017
3	Nonesterified Fatty Acids (NEFA)IBA 03/2016 - 01/2009
3	HDL LipoproteinsIBA 12/2014 - 04/2006
3	CalciumIBA 11/2012 - 01/2010
2	Biological ProductsIBA 11/2022 - 07/2007
2	nasIBA 01/2021 - 01/2021
2	RNA (Ribonucleic Acid)IBA 01/2021 - 08/2012
2	Messenger RNA (mRNA)IBA 01/2021 - 08/2014
2	Triglycerides (Triacylglycerol)IBA 01/2020 - 09/2006
2	Chemokine CCL2 (Monocyte Chemoattractant Protein 1)IBA 01/2019 - 01/2017
2	Troponin T (Troponin T1)IBA 01/2019 - 10/2016
2	Pravastatin (Pravachol)FDA LinkGeneric 09/2018 - 01/2017
2	Immunologic Factors (Immunomodulators)IBA 01/2018 - 06/2012
2	fibroblast growth factor 21IBA 12/2017 - 05/2015
2	Phosphocreatine (Neoton)IBA 03/2016 - 12/2009
2	Metformin (Glucophage)FDA LinkGeneric 05/2015 - 02/2004
2	HDL CholesterolIBA 12/2014 - 09/2006
2	Testosterone (Sustanon)FDA Link 11/2010 - 07/2007
2	Ritonavir (Norvir)FDA Link 06/2010 - 07/2009
2	ResistinIBA 08/2008 - 07/2007
1	IgA receptor (protein B)IBA 01/2022
1	AntibodiesIBA 01/2022
1	pro-brain natriuretic peptide (1-76)IBA 01/2022
1	Immunoglobulin A (IgA)IBA 01/2022
1	Immunoglobulin G (IgG)IBA 01/2022
1	COVID-19 VaccinesIBA 01/2022
1	Mineralocorticoid Receptors (Mineralocorticoid Receptor)IBA 01/2022
1	Integrase InhibitorsIBA 12/2021
1	Biological FactorsIBA 01/2021
1	lamin CIBA 01/2021
1	Insulin-Like Growth Factor Binding ProteinsIBA 01/2021
1	DNA (Deoxyribonucleic Acid)IBA 11/2020
1	InflammasomesIBA 10/2020
1	NLR ProteinsIBA 10/2020
1	Tenofovir (Viread)FDA Link 01/2020
1	Procollagen Type IIBA 01/2020
1	Protons (Proton)IBA 12/2019
1	Lipocalin-2IBA 01/2019
1	omega-Chloroacetophenone (Mace)IBA 01/2019
1	Brain Natriuretic Peptide (Natrecor)FDA Link 01/2019
1	Apolipoproteins E (ApoE)IBA 01/2019

Therapy/Procedure

29	Therapeutics 10/2022 - 11/2002
6	Art Therapy 10/2022 - 09/2012
5	Highly Active Antiretroviral Therapy (HAART) 01/2019 - 04/2005
1	Sodium-Restricted Diet (Diet, Sodium Restricted) 01/2019